In picosecond laser cosmetic treatments, the choice of wavelength directly determines the precision and final outcome of the treatment. Different types of pigmentation problems, due to their varying depths within the skin tissue, exhibit significantly different absorption efficiencies for specific wavelengths of laser light. Understanding this is fundamental to developing personalized treatment plans.
532nm, 755nm, 1064nm: A Detailed Understanding of the Three Major Wavelengths of Picosecond Lasers
Currently, the mainstream picosecond laser wavelengths used in clinical practice mainly include 532nm, 755nm, and 1064nm, each with unique physical characteristics and tissue penetration depth.
The 532nm wavelength belongs to the green light in the visible spectrum. Its characteristic is that it is easily absorbed by melanin and red pigments, but due to its short wavelength, its penetration depth is limited, primarily acting on the epidermis. This makes the 532nm picosecond laser an ideal choice for treating epidermal pigmentation problems, and it also has good removal effects on red and yellow tattoos.
The 755nm alexandrite laser has a longer wavelength, capable of penetrating to the boundary between the epidermis and dermis. It has a high absorption coefficient for melanin while causing less thermal damage to surrounding normal tissue. This wavelength is widely used in the field of pigmentation treatment, treating both epidermal pigmentation and some dermal pigmentation lesions.
The 1064nm Nd:YAG laser has the deepest penetration of the three wavelengths, reaching the deep dermis. Because melanin absorbs relatively little of it, the epidermal barrier competes less for laser energy, so the energy can be safely delivered to deeper tissues. It is especially suitable for treating deeper pigmentation lesions and removing black or blue tattoos for people with darker skin tones.
Choosing the Appropriate Wavelength for Treating Epidermal Pigmentation Disorders
For pigmentation disorders located in the epidermis, such as freckles, solar lentigines, and café-au-lait spots, 532nm and 755nm are the primary choices.
Treatment of freckles and solar lentigines is generally effective, especially for patients with Fitzpatrick type I-III skin, lesions with a clear contrast to normal skin, and well-defined borders. Clinically, 532nm or 755nm picosecond lasers are commonly used, with the treatment endpoint usually defined by the appearance of a mild whitening reaction.
For café-au-lait spots and freckle-like nevi, picosecond lasers can use ultra-short pulses to precisely break down melanin, providing a highly efficient treatment process. However, please note that these pigmented lesions still have a potential recurrence rate, requiring thorough communication between the doctor and patient before treatment to establish reasonable expectations.
It is important to note that for patients with lighter-colored lesions or concurrent melasma, regardless of the wavelength chosen, more careful attention must be paid to parameter settings and treatment intervals for optimal results and subsequent maintenance.

How to Choose the Appropriate Wavelength for Dermal Hyperpigmentation?
When ectopic melanocytes are present in the dermis, the nature of the pigmentation problem is fundamentally altered. Ota's nevus, blue nevus, and Ito's nevus are typical examples of dermal hyperpigmentation. The pigment granules in these lesions are located in the middle to deep dermis, thus requiring wavelengths with stronger penetration to be effective.
The 1064nm wavelength, with its superior penetration depth, has become the cornerstone of dermal hyperpigmentation treatment. Its energy can penetrate the entire epidermis and dermis, reaching the location of deep ectopic melanocytes. Studies have shown that picosecond 1064nm laser treatment for Ota's nevus is significantly effective, with a higher lesion clearance rate per treatment and fewer treatment sessions required.
Blue nevus is an extremely common dermal pigmentation problem in Asian populations, typically appearing on the cheekbones and around the eyes. The pigment cells in these lesions are located in the superficial to middle dermis, both 755nm and 1064nm are treatment options.
- The 755nm wavelength has a higher absorption efficiency for melanin, often resulting in more noticeable fading of pigmentation after a single treatment.
- However, the 1064nm wavelength causes less stimulation to epidermal melanocytes, leading to a relatively lower risk of post-treatment hyperpigmentation.
For patients with darker skin tones or a history of hyperpigmentation, the 1064nm wavelength is recommended as the first choice, using a low-energy, multiple-treatment approach to gradually remove dermal pigmentation and achieve the best treatment results.
Wavelength Decisions for Melasma Treatment
Melasma is a challenging condition to treat due to its complex etiology and significantly different treatment strategies compared to other pigmentary disorders. Currently, the 1064nm picosecond laser is generally considered the optimal choice for treating melasma. The 1064nm wavelength penetrates deep into the dermis, targeting deep pigmentation with minimal epidermal damage, thus reducing the risk of post-inflammatory hyperpigmentation (PIH). It is particularly suitable for darker skin tones (Fitzpatrick types IV-VI) and minimizes post-treatment pigmentation changes.
While the 1064nm laser is favored for its safety and applicability to various skin types, the 755nm laser can also be used, but requires careful operation to avoid triggering PIH as it is more readily absorbed by melanin. Therefore, physicians should pay close attention to adjusting the energy parameters during treatment.
The Influence of Skin Color Type on Wavelength Selection
Besides pigmentation depth, a patient's skin type is also a crucial factor in wavelength selection. The Fitzpatrick skin type classification reflects differences in skin response to ultraviolet radiation and pigmentation tendency, directly impacting the safety of laser treatment.
For Fitzpatrick types I-III (lighter skin), all three wavelengths can be safely used. Temporary erythema and thin crusts after 532nm wavelength treatment typically subside within one week, with a low incidence of pigmentation. These patients can also safely receive 755nm or 1064nm treatment, choosing freely based on pigmentation depth.
For Fitzpatrick types IV-VI (darker skin), the basal layer of the epidermis contains a large number of melanin granules. These endogenous pigments compete for laser energy. Using a 532nm wavelength, the competitive absorption of energy by epidermal melanin may lead to epidermal damage and post-inflammatory hyperpigmentation, or even hypopigmentation. Therefore, darker skin patients should preferentially choose the 1064nm wavelength, which has a low melanin absorption coefficient, effectively reducing the risk of epidermal damage. If 755nm is to be used, the energy density should be appropriately reduced, and treatment should be stopped if mild erythema occurs.
The immediate reaction after picosecond laser treatment is a crucial indicator of whether the energy and wavelength are appropriate. A uniform grayish-white reaction after epidermal pigmentation treatment indicates effective pigment breakdown; if only erythema appears without whitening, higher energy or a different wavelength may be necessary. Dermal pigmentation treatment typically does not produce an immediate visible reaction; observation of pigment metabolism over 1-3 months is required.
Furthermore, inquiring about treatment history is extremely important. Patients who have previously received laser treatment, especially those with a history of post-inflammatory hyperpigmentation, should consult a physician beforehand to choose a more conservative wavelength and parameters to avoid potential side effects.
In actual clinical practice, the selection of wavelength needs to comprehensively consider the patient's skin type, skin damage characteristics, and treatment history. For patients with darker skin tones, the 1064nm wavelength, with its deeper penetration, should be prioritized to reduce the risk of hypopigmentation due to competitive absorption by epidermal pigment.
Furthermore, the setting of treatment parameters is equally crucial. The same wavelength will produce different therapeutic effects at different energies, spot sizes, and frequencies. Physicians should adjust parameters in real time by observing the endpoint reaction during the procedure (such as the degree of whitening), rather than blindly using recommended parameters.
High-end picosecond laser devices with multiple wavelengths available
A single wavelength can only address a limited range of skin problems. This has led to the growing market demand and acceptance for the combined use of multiple wavelengths. This not only saves on the cost and space utilization of purchasing multiple devices but also enhances the professionalism of your services. After all, a leading-edge device can significantly boost the competitiveness and reputation of your clinic or beauty salon.
Newangie has nearly twenty years of experience in the research, development, and export of picosecond laser devices, with clients in numerous countries worldwide. The treatment effects of its devices have received high praise from clients (clinics, beauty salons, spas, distributors, etc.) around the world.
One device is equipped with multiple working heads, providing diverse solutions for various skin conditions and tattoo colors.
- 532 nm: Effective for red, orange, and yellow tattoo inks, as well as surface pigmentation.
- 585 nm: Suitable for red tattoos, vascular lesions, and port-wine stains.
- 650 nm: Improves removal of stubborn green and yellow tattoo pigments.
- 755 nm: Commonly used for treating pigmented lesions, removing superficial spots, and improving skin tone.
- 1064 nm: Ideal for treating deeper pigmented lesions, darker skin tones, and removing black or blue tattoos.
Unique features of Newangie 350ps TruePico Laser Machine
- Adjustable Spot Size: Operators can easily adjust the spot size directly on the handpiece of our 350Ps TruePico pico laser, providing more precise treatment for patients with simple and convenient operation.
- Rugged and Durable: The light guide arm of our 350Ps TruePico laser is imported from South Korea and made of stainless steel, enhancing corrosion resistance and extending its service life. It can also rotate 360°, providing operators with great convenience and flexibility.
- High Precision: Our picosecond laser's beam guiding system ensures optimal laser energy transmission and minimizes light loss, providing patients with precise and efficient treatment.
- Versatile Applications: Whether you want to remove tattoos, blemishes, pigmentation, or rejuvenate your skin and delay skin aging, our picosecond laser can meet the diverse skin needs of our clients.
The selection of the three wavelengths for picosecond lasers is essentially a precise matching process-choosing a wavelength with appropriate penetration power based on the depth of pigmentation to find the optimal balance between safety and efficacy.
If you are interested in learning about multi-wavelength picosecond laser technology and equipment, please contact us. We will provide you with a detailed brochure of picosecond laser equipment and help answer your questions about picosecond treatment and postoperative precautions.






